*Himalaya Platenza*

– *Description*: _Sci-Vedic_ hematoprotective formulation specifically developed to increase platelet count (thrombocytopoiesis) and reverse thrombocytopenia. Core actives include _Carica papaya_ leaf extract, _Guduchi (Tinospora cordifolia)_, _Maricha (Piper nigrum)_, and _Bhudhatri (Phyllanthus niruri)_. Available as tablets and syrup. _Carica papaya_ provides bioactive compounds like papain, kaempferol, quercetin, and chymopapain that exhibit antiviral, anti-inflammatory, and platelet-enhancing properties.

– *Key Benefits*:

– *Increases Platelet Count*: Clinically shown to elevate platelet levels in thrombocytopenia associated with dengue, malaria, and other viral infections. _Carica papaya_ leaf extract accelerates the rate of platelet count recovery, increases megakaryocyte activity, and reduces peripheral platelet destruction. RCT data show significant platelet rise by Day 3–5 vs placebo and reduced need for platelet transfusion.

– *Particularly in Dengue, Malaria & Viral Infections*: Addresses virus-induced thrombocytopenia by inhibiting viral replication of NS3/NS5 proteins and modulating immune-mediated platelet destruction. Supports recovery in dengue fever (DF), dengue hemorrhagic fever (DHF), malaria, chikungunya, and other febrile illnesses causing platelet drop.

– *Strengthens Host Immune System*: _Guduchi_ and _Bhudhatri_ are potent immunomodulators that enhance macrophage function, boost WBC response, and improve host defense against pathogens. Reduces fever-related complications and promotes faster convalescence.

– *Hepatoprotective & Anti-inflammatory*: _Bhudhatri_ and _Guduchi_ protect liver, support detoxification, and reduce inflammatory cytokine surge common in viral infections. _Maricha_ improves bioavailability of other actives.

– *Reduces Bleeding Risk*: By restoring platelet count and function, helps manage petechiae, bleeding gums, nosebleeds, and internal bleeding risk associated with severe thrombocytopenia.

– *Action on Doshas*: Pacifies _Pitta_ and _Kapha_ in _Rakta_ and _Majja Dhatu_. _Tikta-Kashaya Rasa_ reduces _Pitta_-induced inflammation and viral load; _Ushna Virya_ clears _Kapha_ stagnation. Nourishes _Rakta Dhatu_ to support healthy hematopoiesis.

– *Usage*:

– *Tablets*: Adults 1-2 tablets twice daily, or as directed by physician.

– *Syrup*: 5-10 years: 5-10ml twice daily; 10-18 years: 10-15ml twice daily; Adults: 15-20ml twice daily.

– Take after meals. Continue until platelet count normalizes and as advised by physician.

– *Safety*: Generally well-tolerated. Rare mild digestive discomfort. Avoid in pregnancy without medical supervision due to uterine stimulant concerns with _Carica papaya_. Not recommended with BPH/prostate disorders. Do not self-medicate in severe dengue – use as adjunct to standard medical care.

*Clinical Note*: Thrombocytopenia is a hallmark of dengue with platelet counts <150,000/µL increasing risk of hemorrhage. _Carica papaya_ leaf extract has demonstrated efficacy in elevating platelets, reducing hospitalization days, and decreasing transfusion requirements without significant adverse events. 6cad02d3

Need this formatted for a physician’s dengue management protocol or a 100ml syrup patient leaflet?